兰江风 【副教授】

姓名 兰江风 性别 照片
职称 副教授 学位 博士
电话 13871570938 邮箱 lanjiangfeng@mail.hzau.edu.cn
工作单位 华中农业大学水产学院
研究方向 无脊椎动物先天免疫:病原逃逸机制、免疫识别、信号转导与调控、免疫效应分子的筛选与功能分析
教育经历 2009.9-2014.6, 山东大学 生命科学学院, 动物学  理学博士, 导师:王金星, 研究方向:无脊椎动物先天免疫
2005.9-2009.6,湖南科技大学 生命科学学院, 生物技术  理学学士 
主要职历 2017.12-今       华中农业大学  水产学院  副教授
2017.12-今       耶鲁大学      访问学者
2014.7 -2017.12  华中农业大学  水产学院  讲师  
科研成果

科研项目:

1、国家自然基金青年基金,31502199,抑制素2介导克氏原螯虾应对白斑病毒感染的分子机制研究,2016.1-2018.1220 万元,主持-在研

2、湖北省自然科学基金面上项目,2017CFB550, Ficolin参与Toll信号通路调控的分子机制研究,2018.1-2019.12, 3万,主持-在研

3中央高校自主创新资金-拔尖人才培育专项,两种重要凝集素在Toll信号调控中的功能研究2016.8-2018.830万,主持-在研

4、浙江淡水水产研究所开放课题-重大项目,ZJK201804关键凝集素参与Toll信号调控的分子机制研究,2018.1-2020.12 10万,主持-在研

5中央高校自主创新资金-青年专项,2662015QC019白斑病毒核酸酶抑制宿主免疫应答的机制研究,2015.1-2016.128万,主持-已结题

6、中央高校自主创新资金-启动专项,2662014BQ031,克氏原螯虾L-lectin的免疫功能研究,2014.9-2015.125万,主持-已结题

7农业部渔用药物创制重点实验室开放基金,201401,抗白斑病毒抗菌肽的筛选及其抗病毒活性基序的初步探讨, 2015.1-2016.124万,主持-已结题


论文列表: #并列第一作者,*通讯作者

1. Qin Z, Babu VS, Wan Q, Muhammad A, Li J, Lan J*, Lin L*. Antibacterial activity of hemocyanin from red swamp crayfish (Procambarus clarkii). Fish Shellfish Immunol. 2018 Feb 7;75:391-399. JCR 1区

2. Sun JJ#, Lan JF#, Zhao XF, Vasta N, Wang JX*, Binding of a C-type lectin's coiled-coil domain to the Domeless receptor directly activates the JAK/STAT pathway in the shrimp immune response to bacterial infection. PLoS Pathog. 2017 Sep 20;13(9):e1006626. doi: 10.1371/journal.ppat.1006626. JCR 1区, IF=6.608.

3. Zhou J, Zhao S, Fang WH, Zhou JF, Zhang JX, Ma H, Lan JF*, Li XC. Newly identified invertebrate-type lysozyme (Splys-i) in mud crab (Scylla paramamosain) exhibiting muramidase-deficient antimicrobial activity. Dev Comp Immunol. 2017 Sep;74:154-166. JCR1区, IF=3.2.

4. Dai YJ#, Hui KM#, Zhang YH, Liu Y, Wang YQ, Zhao LJ, Lin L, Chai LQ*, Wei Shun*, Lan JF*. Three STATs are involved in the regulation of the expression of Antimicrobial peptides in the Triangle sail mussel, Hyriopsis cumingii. Fish Shellfish Immunol. 2017 Feb, 63: 181-188. JCR 1, IF=3.025.

5. Dai YJ, Wang YQ, Zhang YH, Liu Y, Li JQ, Wei S, Zhao LJ, Zhou YC, Lin L*, Lan JF*. The role of ficolin-like protein (PcFLP1) in the antibacterial immunity of red swamp crayfish (Procambarus clarkii). Mol Immunol., 2017, 81: 26-34. JCR 3区,IF=3.375.

6. Lan JF, Zhao LJ, Wei S, Wang Y, Lin L, Li XC. PcToll2 positively regulates the expression of antimicrobial peptides by promoting PcATF4 translocation into the nucleus. Fish Shellfish Immunol. 2016 Sep 10;58:59-66. JCR 1, IF=3.025.

7. Lan JF, Wei S, Wang YQ, Dai YJ, Tu JG, Zhao LJ, Li XC, Qin QW, Chen N*, Lin L*. PcToll3 was involved in anti-Vibrio response by regulating the expression of antimicrobial peptides in red swamp crayfish, Procambarus clarkii. Fish Shellfish Immunol, 2016 Aug 13, 57 : 17-24. JCR 1, IF=3.025.

8. Sun JJ, Lan JF*, Xu JD, Niu GJ, Wang JX*. Suppressor of cytokine signaling 2 negatively regulates the expression of antimicrobial peptides by affecting the Stat transcriptional activity in shrimp Marsupenaeus japonicus. Fish Shellfish Immunol. 2016 Aug 2;56:473-482. JCR 1, IF=3.025.

9. Wang Y, Chen N, Abeer M. Hegazy, Liu XD, Wu ZX , Liu XQ, Zhao LJ, Qin QW, Lan JF*, Lin L*. Autophagy induced by Snakehead fish vesiculovirus inhibited its replication in SSN-1 cell line. Fish Shellfish Immunol, 2016 Jun 13;55:415-422. JCR 1, IF=3.025.

10. Zhao LL, Wang YQ, Dai YJ, Zhao LJ, Qin QW, Lin L, Ren Q*, Lan JF*. A novel C-type lectin with four CRDs is involved in the regulation of antimicrobial peptide gene expression in Hyriopsis cumingii. Fish Shellfish Immunol, 2016 Jun 7;55:339-347. JCR 1, IF=3.025.

11. Zhao LL, Jin M, Li XC, Ren Q*, Lan JF*. Four C1q domain-containing proteins involved in the innate immune response in Hyriopsis cumingii. Fish Shellfish Immunol. 2016 Jun 7;55:323-331. JCR 1, IF=3.025.

12. Dai YJ, Wang YQ, Zhao LL, Qin ZD, Yuan JF, Qin QW, Lin L*, Lan JF*. A novel L-type lectin was required for the multiplication of WSSV in red swamp crayfish (Procambarus clakii). Fish Shellfish Immunol, 2016 May 18;55:48-55. JCR 1, IF=3.025.

13. Tu JG #, Chen WJ #, Fu XZ, Lin Q, Chang OQ, Zhao LJ, Lan JF*, Li NQ*, Lin L*.Susceptibility of Chinese perch brain (CPB) cell and Mandarin fish to Red-spotted grouper nervous necrosis virus (RGNNV) infection. Int J Mol Sci. 2016 May 19;17(5). pii: E740. JCR 3区, IF=3.257.

14. Wang Z#, Chen YH#, Dai YJ#, Tan JM, Huang Y, Lan JF*, Qian Ren*.A novel vertebrates Toll-like receptor counterpart regulating the anti-microbial peptides expression in the freshwater crayfish, Procambarus clarkii. Fish Shellfish Immunol. 2015 Jan 5;43(1):219-229. JCR 1, IF=3.025.

15. Ding ZF#, Ren J#, Tan JM, Wang Z, Yin SW, Huang Y, Huang X, Wang W, Lan JF*, Qian Ren*.Characterization of two novel ADP ribosylation factors from giant freshwater prawn Macrobrachium rosenbergii and their responses to WSSV challenge.Dev Comp Immunol. 2015 Jan;48(1):204-9. JCR 1区,IF=3.62.

16. Liu N#, Lan JF #, Sun JJ#, Jia WM, Zhao XF, Wang JX*.A novel crustin from Marsupenaeus japonicus promotes hemocyte phagocytosis. Dev Comp Immunol. 2014 Dec 3;49(2):313-322. JCR 1区,IF=3.62.

17. Ren Q#*, Lan JF#, Zhong X#, Song XJ, Ma F, Hui KM,Wang W, Yu XQ*, Wang JX*. A novel Toll like receptor with two TIR domains (HcToll-2) is involved in regulation of antimicrobial peptide gene expression of Hyriopsis cumingii. Dev Comp Immunol. 2014 Jul;45(1):198-208. JCR 1区,IF=3.62.

18. Zhu L#, Lan JF#, Huang YQ#, Zhang C, Zhou JF, Fang WH*, Yao XJ, Wang H, Li XC*. SpALF4: a newly identified anti-lipopolysaccharide factor from the mud crab Scylla paramamosain with broad spectrum antimicrobial activity. Fish and Shellfish Immunology. 2014 Jan;36(1):172-80. JCR 1, IF=3.025.

19. Lan JF, Zhou J, Zhang XW, Wang ZH, Zhao XF, Ren Q, Wang JX*. Characterization of an immune deficiency homolog (IMD) in shrimp (Fenneropenaeus chinensis) and crayfish (Procambarus clarkii). Dev Comp Immunol. 2013 Dec;41(4):608-17. JCR 1区,IF=3.62.

20. Lan JF, Li XC, Sun JJ, Gong J, Wang XW, Shi XZ, Shi LJ, Weng YD, Zhao XF, Wang JX*. Prohibitin Interacts with envelope proteins of white spot syndrome virus and prevents infection in the red swamp crayfish, Procambarus clarkii. J Virol. 2013 Dec;87(23):12756-65. JCR 2区, IF=4.606.

21. Du ZQ#, Lan JF#, Weng YD, Zhao XF, Wang JX*. BAX inhibitor-1 silencing suppresses white spot syndrome virus replication in red swamp crayfish, Procambarus clarkii. Fish Shellfish Immunol. 2013 Jul;35(1):46-53. JCR 1, IF=3.025.

22. Sun JJ, Lan JF, Shi XZ, Yang MC, Niu GJ, Ding D, Zhao XF, Yu XQ, Wang JX*. β-Arrestins Negatively Regulate the Toll Pathway in Shrimp by Preventing Dorsal Translocation and Inhibiting Dorsal Transcriptional Activity. J Biol Chem. 2016 Apr 1;291(14):7488-504. JCR 2, IF= 4.258.

23. Shi XZ, Feng XW, Sun JJ, Yang MC, Lan JF, Zhao XF, Wang JX*. Involvement of a LysM and putative peptidoglycan-binding domain-containing protein in the antibacterial immune response of kuruma shrimp Marsupenaeus japonicus. Fish Shellfish Immunol. 2016 Jul;54:489-98. JCR 1, IF=3.025.

24. Zheng FF, Asim M, Lan JF, Zhao LJ, Wei S, Chen N, Liu XL, Zhou Y, Lin L*. Molecular Cloning and Functional Characterization of Mannose Receptor in Zebra Fish (Danio rerio) during Infection with Aeromonas sobria. Int J Mol Sci. 2015 May 15;16(5):10997-1012. JCR 3区, IF=3.257.

25. Hu XQ, Fu XZ, Li NQ, Dong XX, Zhao LJ, Lan JF, Ji W, Zhou WD, Ai TS, Wu SQ, Lin L*. Transcriptomic analysis of Mandarin fish brain cells infected with infectious spleen and kidney necrosis virus with an emphasis on retinoic acid-inducible gene 1-like receptors and apoptosis pathways. Fish Shellfish Immunol. 2015 May 14. pii: S1050-4648(15)00224-7. JCR 1, IF=3.025.

26. Dong XX, Qin ZD, Hu XQ, Lan JF, Yuan GL, Asim M, Zhou Y, Ai TS, Mei J, Lin L*. Molecular cloning and functional characterization of cyclophilin A in yellow catfish (Pelteobagrus fulvidraco). Fish Shellfish Immunol. 2015 Apr 13. pii: S1050-4648(15)00154-0. JCR 1, IF=3.025.

27. Yang HT, Yang MC, Sun JJ, Guo F, Lan JF, Wang XW, Zhao XF, Wang JX*. Catalase eliminates reactive oxygen species and influences the intestinal microbiota of shrimp. Fish Shellfish Immunol. 2015 Aug 24;47(1):63-73. JCR 1, IF=3.025.

28. Sun JJ, Lan JF, Shi XZ, Yang MC, Yang HT, Zhao XF, Wang JX*. A fibrinogen-related protein (FREP) is involved in the antibacterial immunity of Marsupenaeus japonicus. Fish Shellfish Immunol. 2014 Aug;39(2):296-304. JCR 1, IF=3.025.

29. Shi XZ, Zhou J, Lan JF, Jia YP, Zhao XF, Wang JX*. A Lysin motif (LysM)-containing protein functions in antibacterial responses of red swamp crayfish, Procambarus clarkii. Dev Comp Immunol. 2013 Jul-Aug;40(3-4):311-9. JCR 1区,IF=3.62.

30. Mu Y, Lan JF, Zhang XW, Wang XW, Zhao XF, Wang JX*. A vector that expresses VP28 of WSSV can protect red swamp crayfish from white spot disease. Dev Comp Immunol. 2012 Feb;36(2):442-9. JCR 1区,IF=3.62.

31. Li XC, Du ZQ, Lan JF, Zhang XW, Mu Y, Zhao XF, Wang JX*. A novel pathogen-binding gC1qR homolog, FcgC1qR, in the Chinese white shrimp, Fenneropenaeus chinensis. Dev Comp Immunol. 2012 Feb;36(2):400-7. JCR 1区,IF=3.62.

32. Li XC, Zhang RR, Sun RR, Lan JF, Zhao XF, Wang JX*. Three Kazal-type serine proteinase inhibitors from the red swamp crayfish Procambarus clarkii and the characterization, function analysis of hcPcSPI2. Fish Shellfish Immunol. 2010 May-Jun;28(5-6):942-51. JCR 1, IF=3.025.

33. Dawar FU, Tu J, Xiong Y, Lan JF, Dong XX, Liu X, Khattak MN, Mei J, Lin L. Chemotactic Activity of Cyclophilin A in the Skin Mucus of Yellow Catfish (Pelteobagrus fulvidraco) and Its Active Site for Chemotaxis. Int J Mol Sci. 2016 Aug 29;17(9). pii: E1422. JCR 3区,IF=3.257.

34. Sun L, Yi L, Zhang C, Liu X, Feng S, Chen W, Lan JF, Zhao L, Tu J, Lin L. Glutamine was required for snakehead fish vesiculovirus (SHVV) propagation via replenishing the tricarboxylic acid cycle. J Gen Virol. 2016 Sep 6. doi: 10.1099/jgv.0.000597. JCR 2区,IF=3.192.

35. Chen W, Yi L, Feng S, Liu X, Asim M, Zhou Y, Lan JF, Jiang S, Tu J, Lin L. Transcriptomic profiles of striped snakehead fish cells (SSN-1) infected with red-spotted grouper nervous necrosis virus (RGNNV) with an emphasis on apoptosis pathway. Fish Shellfish Immunol. 2016 Nov 30;60:346-354. JCR 1, IF=3.025.

36. Zhang Z, Yu A, Lan JF, Zhang Y, Zhang H, Li Y, Hu M, Cheng J, Wei S, Lin L. Draft Genome Sequence of an Attenuated Streptococcus agalactiae Strain Isolated from the Gut of a Nile Tilapia (Oreochromis niloticus). Genome Announc. 2017 Feb 9;5(6). pii: e01627-16.

37. Zhang Z, Yu A, Lan JF, Zhang H, Hu M, Cheng J, Zhao L, Lin L, Wei S. GapA, a potential vaccine candidate antigen against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Fish Shellfish Immunol. 2017 Feb 17. pii: S1050-4648. JCR 1, IF=3.025.

38. Ren Q, Wang C, Jin M, Lan JF, Ye T, Hui K, Tan J, Wang Z, Wyckoff GJ, Wang W, Han GZ. Co-option of bacteriophage lysozyme genes by bivalve genomes. Open Biol. 2017 Jan;7(1). pii: 160285. JCR 2区,IF= 4.822.

39. Chen W, Yi L, Feng S, Liu X, Asim M, Zhou Y, Lan JF, Jiang S, Tu J, Lin L. Transcriptomic profiles of striped snakehead fish cells (SSN-1) infected with red-spotted grouper nervous necrosis virus (RGNNV) with an emphasis on apoptosis pathway. Fish Shellfish Immunol. 2017 Jan;60:346-354. JCR 1, IF=3.025.

40. Jin J, Wang Y, Wu Z, Hergazy A, Lan JF, Zhao L, Liu X, Chen N, Lin L. Transcriptomic analysis of liver from grass carp (Ctenopharyngodon idellus) exposed to high environmental ammonia reveals the activation of antioxidant and apoptosis pathways. Fish Shellfish Immunol. 2017 Feb 21. JCR 1, IF=3.025.

41. 刘小玲,王虹,樊启学,兰江风*,林蠡*,黄颡鱼甘露糖受体基因的克隆和功能分析.水产学报 2017.

42. 兰江风, 代云佳, 林蠡*,养殖克氏原螯虾体内白斑综合征病毒的绝对定量分析. 水产学报 2016 40 (3) 318-324.

43. 魏顺,张泽,李宇辉,胡敏强,余岸艮,张华,兰江风,张志,颜远义,林蠡*,广东地区吉富罗非鱼无乳链球菌的流行情况与耐药性. 水产学报 2016 40 (3) 503-511.

专利

1. 王金星、兰江风、赵小凡;克氏原螯虾抑制素1基因及其编码的抑制素1蛋白及其应用;发明专利,授权号:ZL201310289986.4 授权日期2014.11.26

2. 介邓飞、魏萱、兰江风、吴兰兰、王烨;一种类球形水果透射高光谱成像无损检测技术;应用新型专利,授权号:ZL201520776473.0 授权日期:2016.2.

备注 2018年  拟招收学术硕士研究生2人,专业硕士研究生1人。欢迎对无脊椎动物先天免疫感兴趣的同学加入。
因18年不在国内,请微信联系(微信号同手机号)。